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Description
PD patients frequently exhibit dysbiosis, characterized by: Reduced short-chain fatty acidproducing bacteria (e.g., Faecalibacterium )
Delving into specific models, T-cell-specific HGK conditional knockout mice (also referred to as T-HGK cKO) with a deficiency in the leptin receptor exhibit reduced Th17 differentiation
Fuentes-Santamara et al., 2017)
Continued research into natural MnSOD regulation and the rational development of mimetics may yield effective strategies for managing oxidative stress-related diseases, particularly those in which direct genetic modulation is impractical
