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Plant Physiol Biochem 185:123131 Zeng H, Bai Y, Wei Y, Reiter RJ, Shi H (2022) Phytomelatonin as a central molecule in plant disease resistance

Its key enzymes and the entire pathway not only act as driving factors of tumor development, but also provide theoretical support and potential targets for targeted therapy and its combination with immunotherapy

MASLD is the most common chronic liver disease and comprises histopathological disorders that range from the accumulation of triglycerides in the liver (steatosis) to non-alcoholic steatohepatitis (MASH) characterized by the presence of inflammation and fibrosis in the liver [14]

Synthesized from methionine and adenosine tri-phosphate (ATP), SAMe serves as the principal methyl group donor in countless transmethylation reactions and serves as a key precursor feeding into the transsulfuration pathway (Villanueva and Halsted, 2004