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DOI: 10.1212/WNL.0b013e311fc619bc Kaeser PS, Regehr WG (2017): The readily releasable pool of synaptic vesicles

RRM2 is aberrantly expressed in human tumors such as breast cancer (21, 22), gastric cancer (23), adrenocortical cancer (24), pancreatic cancer (25) and bladder cancer (26)

Jain, S., Winuprasith, T

2) This activation triggers various signaling pathways that support tumor cell proliferation and survival, including the MAPK/ERK, Wnt/Apc/-catenin, epidermal growth factor receptor (EGFR), in addition to pathways related to cell migration like PI3K/AKT, osteopontin, matrix metalloproteinases (MMP), and E-cadherin, among others [83,84,85,86,87]
