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Nery FG, Weber WA, Blom TJ, Welge J, Patino LR, Strawn JR, et al

In vitro assays also document inhibitory effects on CYP1A2, CYP2C9, and CYP3A4, suggesting that high-dose or chronic exposure may alter the pharmacokinetics of drugs with narrow therapeutic windows (Kaci et al., 2023)

The study challenges the notion of redox compartmentalization in MLOs, suggesting that their redox environment mirrors that of their surroundings, likely due to the lack of physical barriers and similar partitioning of GSH and GSSG.

Clinical trials conducted on patients with congenital retinal diseases such as Leber hereditary optic neuropathy have shown promising results with direct gene medical application in the treatment of optic neuropathy [124,125]