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To isolate sources and chemistries, apply genetic/pharmacologic separation: NOX and NOS isoform-selective inhibitors/knockdowns, modulation of CBS/CSE/3-MST for sulfur pathways and controlled iron chelation or loading to test Fenton dependence

Recently, researchers have developed albumin-based MnO 2 NPs for pH-responsive MR imaging and enhanced radiotherapy of breast cancers (Prasad et al., 2014

These are ultimately two different scenarios involving completely different chemistries
