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Description
In a tramadol-induced hepatotoxicity rat model, supplemental lycopene at 15 mg/kg body weight for 15 days mitigated the hepatotoxicity by increasing antioxidant activity, reducing fatty acid breakdown and necrosis, lipid peroxidation, inhibiting DNA fragmentation, and apoptosis [115]

Among these emerging radiosensitizers, gold nanoparticles (Au NPs) are particularly attractive because of their strong interaction with the radiation (Au has a high atomic number of 79), excellent chemical stability and inertness and good biocompatibility (low toxicity) 18,19,20,21

For example, severe vitamin C deficiency causes scurvy, which consists of connective tissue degeneration and is lethal when left untreated

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