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Among them, GSTM1 showed stable interactions with multiple compounds in molecular docking analyses, suggesting potential druggability

Mobou, E

doi: 10.3390/jcm6090086 6 AloyB.Launay-VacherV.BleibtreuA.BortolottiP.FaureE.FilaliA.et al

In oxaliplatin-induced CIPN models, melatonin prevented the loss of mitochondrial membrane potential (m), promoted nerve regeneration in oxaliplatin-challenged Neuro-2a cells and prevented the loss of nitrosation of proteins and antioxidant enzymes by improving nitrooxidative stress mediated by the chemotherapeutic agent oxaliplatin [45] without interfering with oxaliplatin cytotoxic activity in human colon cancer cell lines