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In addition, carrier-mediated transport ensures high tissue-to-plasma concentration ratios in tissues that depend critically on fatty acid oxidation

If going the amphetamine route in a do-over, I would try lisdexamphetamine due to its much lower blood concentration and longer duration than most other options in that category

in fact, BMI does not provide indications about individuals body composition and adiposity distribution, and today it is well established that abdominal obesity is correlated with increased cardiovascular risk, T2DM, and even some female cancers [37, 3941]
10.1074/jbc.M110.187443 59