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Among the identified ligands, the Calca gene, encoding CGRP, and the Tac1 gene, encoding SP, were of particular interest, as both CGRP and SP are secreted by sensory neurons to mediate various physiological functions
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In the brain itself, changes are less severe: they occur as small sources of nervous fibers decay and accumulation of astrocytes, usually subcortically located, an also round hemorrhages with a torus of glial cells
The evolution of oncology companion diagnostics from signal transduction to immuno-oncology
