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The findings indicated that AST/Bex treatment restrained transcription and activity of the amyloidogenic enzyme BACE1, consequently decreasing A oligomers as well as 80-kDa intracellular APP/A species

NTZ, especially at the higher dose, elicited similar hepatoprotective effects comparable to NAC and 4-PBA, indicating the possible involvement of ER stress modulation in NTZ-elicited hepatoprotective effects

In colorectal cancer, NSUN2 enhances the stability of PHGDH mRNA through m5C methylation, thereby activating the SSP, increasing the intracellular NADH/NAD + and NADPH/NADP + ratios, reducing ROS levels and apoptosis, and promoting tumor cell survival and proliferation (105)