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Description
IDH2 is encoded by the IDH2 gene located on chromosome 15q26.1 and is composed of 12 exons that generate three alternatively spliced mRNAs, each of which encode a distinct protein isoform

Trends Biochem Sci 39:199218

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206 Furthermore, this compound exhibits no cross-resistance with cisplatin in ovarian cancer cells and substantial in vivo activity in P388 leukemia-bearing mice
