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Through NRF2-driven GSH synthesis, tumor cells are protected from oxidative stress, which contributes to chemotherapy resistance by reducing the cytotoxic effects of ROS generated during treatment

The levels of the Beclin-1 and Bcl-2 proteins in endometriotic lesions suggest the existence of an autophagy and apoptosis dysfunction in endometriosis in humans (Li et al., 2021) and induced rodent models (Li et al., 2023)