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10.1073/pnas.0909422107 [DOI] [PMC free article] [PubMed] 146.Denroche HC, Levi J, Wideman RD, Sequeira RM, Huynh FK, Covey SD, et al
However, some results indicated that genetic mutations in the genes encoding copper efflux proteins ATP7A/B could lead to functional impairment, which might impair Cu + efflux within cells, copper overload, and induction of copper related cell death
Oral GHK-Cu is more convenient but faces significant absorption challenges due to enzymatic degradation in the digestive tract
7,8 The amino acid cysteine, a component of glutathione, is rate-limiting for glutathione synthesis and itself acts as a direct antioxidant in plasma
