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Weight Loss Produced by Tesofensine in Patients With Parkinsons or Alzheimers Disease

Beyond simply decreasing hunger, it enhances insulin sensitivity, fine-tunes the hormones and neuronal pathways involved in feeling full, decreases cardiometabolic risk, and consistently produces weight loss
Specifically, by suppressing the activation of nuclear factor B (NF-B), it can effectively downregulate the expression of a series of downstream pro-inflammatory cytokines (such as IL and TNF-)

10.1016/j.rec.2024.01.006 64 MathurM.YehY