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The KD not only promotes the conversion of type IIb skeletal muscle fibers to type IIa fibers and increases the levels of neuromuscular junction remodeling markers, but also facilitates mitochondrial biogenesis, reduces endoplasmic reticulum stress, and enhances protein synthesis and proteasome activity (20)

Acetyl-L-carnitine: This is absorbed in the gut more easily and crosses the blood-brain barrier

10.1002/ptr.5350 [DOI] [PubMed] [Google Scholar] Hyrsova, L

In the aging heart that has been pretreated with acetylcarnitine and exposed to ischemia-reperfusion, the mitochondrial defect due to aging is eliminated, and only the defect due to ischemia is still present, improving the recovery after ischemia-reperfusion to the level of the adult heart [28]