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Transcultural use of narcotic water lilies in ancient Egyptian and Maya drug ritual
In the absence of BAAT activity, as observed in Baat -/- mice, [] detoxification mechanisms such as hydroxylation and sulfation are induced
Journal of neurology
However, it should be taken into account that although the difference in the pKa values of the two acidic groups of 4-hydroxythalidomide is sufficient to ensure selective alkylation of the phenolic group, a reaction may still occur in the imide nitrogen zone given its adequately acidity
