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doi: 10.3390/pharmaceutics10030159

Analysis of tissue sections The cumulative length of epidermal disruptions on 1-cm long sections of fixed tissues was measured at a magnification of 20 and related to the total length of the section

However, if you are taking high-potency individual supplements (like 500 mg+ of Vitamin C), it is much more effective to space them out by at least two hours

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