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doi: 10.1093/jn/108.5.881
doi: 10.1152/physiolgenomics.2001.5.1.21
Owing to concerns about neurotransmitter hyperactivity, SAMe is not recommended in patients with bipolar disorder because of its history of leading to manic and hypomanic states [191]
Park J, Lee DG, Kim B, Park SJ, Kim JH, Lee SR, et al
