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Description
The Preclinical Evidence Base A 2025 systematic review published in peer-reviewed literature identified 544 preclinical articles on BPC-157 published between 1993 and 2024
Indeed, when cultured in absence of serine/glycine, control cells exhibited impaired proliferation, while NKX2-1 overexpressing cells continued to proliferate, showing that increased serine/glycine synthesis enables cancer cells to become independent of exogenous serine for proliferation
The peptide has a half-life of approximately 24 hours, but its downstream effects on AMPK phosphorylation persist for 1224 hours
10.1046/j.1563-2571.2002.01040.x 42
