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doi:10.1530/rep-22-0049

The integrative application of whole-genome sequencing and fragment-based methylation profiling offers a promising path to characterize these programs, but introduces computational and interpretive challenges
at low ratios, they inhibited fibril formation, whereas at higher ratios, they promoted fibrillation

Second, the cross-sectional nature of the study limits our ability to establish causality and exclude the potential reverse causation between biomarkers and diseases, highlighting the need for larger interventional studies
