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The role of glutamine in cancer cell growth Rapidly proliferating cancer cells take up glutamine from plasma via various amino acid transporters, and then it is converted to glutamate in the mitochondria by the two forms of glutaminase: kidney-type glutaminase (GLS)1 and liver-type GLS2 8
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Notwithstanding the likely differences between the substrate specificity between different species, our findings support the consideration of minipig systems as a complementary assay to be used in conjunction with the traditional Ames test
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