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Alcohol has been also found to enhanced production of hydrogen peroxide and OH like species (Dicker and Cederbaum, Oxidative stress dependent TRP channels and pain It is well known that ROS and RNS are produced in several physiological functions, such as mitochondrial and cytochromes P450 activities

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Ozone treatment influences different reactions by enhancing antioxidant enzyme activities, including POD, superoxide dismutase (SOD), and PAL while inhibiting PPO activity