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Description
This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia

Metabolism of such oxo-aldehydes through the glyoxalase system involves conjugation to GSH, catalyzed by glyoxalase 1
Modern delivery systems want to overcome these traditional limitations
Similar results were found in additional experimental models, such as the case of experimental vaccination against cryptococcosis, where the particles protected mice against cryptococcosis in a manner dependent upon mouse strain and cryptococcal species [105] or HBsAg where it increased the antibody formation [106]
