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, Feldstein, A
A pooled CRISPR screen targeting 200 metabolism-related genes in HeLa cells revealed that glutathione peroxidase 4 ( GPX4 ), a crucial ferroptosis suppressor, was selectively essential in lipoprotein-depleted environments, leading to the hypothesis that lipoproteins may confer protection against ferroptosis
2022 Sep 22:nxac179
Sarol and A
