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Description
In normoxia (normal oxygen levels), prolyl hydroxylase hydroxylates HIF-1 at two proline residues (Pro 402 and Pro 564)

It is a hydrocarbon, meaning it is only made of carbon and hydrogen

Insulin helps regulate blood sugar levels when the body cannot produce enough on its own, making it a vital component of diabetes management

This is also one of the reasons for puffy eyes, so the shadows of these puffy eyelids may make the under-eye area appear darker
