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doi: 10.3390/nu15153324

officinalis , is an atypical secoiridoid that possesses a unique six-membered cyclic endoether fragment

The MCU complex is the primary pathway for Ca 2+ entry into mitochondria and is located in the inner mitochondrial membrane (IMM)

Moreover, silibinin mitigates immunosuppression and inhibits tumor progression by limiting PD-L1 protein expression in lung cancer (A549, H292, and H460), papillary thyroid cancer (TPC-1), and nasopharyngeal carcinoma (C666-1) cells [889, 892, 897]
