human glutathione synthetase structure SYNTHESIS GSS General Information | Sino
Description
Figure 4 confirms that there is indeed a hydride transfer equilibrium between the NADPH and the FAD cofactor in that complete exchange of the NADPH dihydronicotinamide Pro-S hydrogen is observed in buffered deuterium oxide in the presence of catalytic amounts of SmTGR C159S

A., Kerper, L
doi: 10.1016/j.febslet.2010.04.067

Nevertheless, promising neuroprotective drugs that were identified as being effective in animal TBI models have all failed in Phase II or Phase III clinical trials
