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Preincubation with NAC was able to prevent HNE and A-induced HNE addition to neprilysin and thus maintain neprilysin activity [64]

Rharass T, Lantow M, Gbankoto A, Weiss DG, Pankov D, Lucas S (2017) Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/-catenin/ROS signaling dependent manner

That said, patients with active diabetes or significant metabolic dysfunction should have any investigational peptide protocol reviewed by their endocrinologist or primary care physician alongside their supervising aesthetic medicine provider

Smith et al
