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We take that seriously

There is also a risk of complications if you take these ADHD medications and certain antidepressant or antipsychotic drugs

no human RCTs have established efficacy

This construct was originally designed for single molecule fluorescence energy transfer experiments (smFRET) in solution, but we also used it for crystallization, because we were unable to reproduce crystallization with the hDPP III construct used in previous studies 17
