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Hence, to obtain a similar sensitivity to the toxicity of methanol and its metabolites as observed in humans, the animals were exposed to nitric oxide (NO), which inhibited the activity of methionine synthase (MS), and resulted in a secondary tetrahydrofolate deficiency, as well as inhibition of the activity of 10-CHO-THFthe decreased activities of these two enzymes lead to impaired metabolism of formate and its accumulation in the body (Chen et al

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Your treatment plan may include ketamine, therapy, lifestyle changes and, if appropriate, Transcranial magnetic stimulation (TMS) or Spravato