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Description
12 Most commonly diagnosed in adults between ages 60 and 80, pernicious anemia can interfere with red blood cell production and may lead to permanent nerve damage if left untreated

This is true whether you opened it yesterday or three months ago: what matters is the date of the first puncture, not how much liquid is left

10.1093/jxb/erv073 16 CriquiM

References Alexandratos, N
