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In the obese state, increased levels of fatty acids and cytokines in circulation induce activation of inflammatory signalling pathways such as STAT3 (signal transducer and activator of transcription 3), p38 MAPK (p38 mitogen-activated protein kinases) and NFkB (nuclear factor kappa-light-chain-enhancer of activated B cells) in metabolic tissue 35,36
Si nos rserves de B12 sont puises, cela passe souvent inaperu pendant longtemps et peut avoir des consquences nfastes sur la sant
