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Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents

A nitroalkene benzoic acid derivative targets reactive microglia and prolongs survival in an inherited model of ALS via NF-kappaB inhibition

10.1016/j.nbd.2004.04.003 27

Superoxide is also easily produced during the radiolysis of water in the presence of oxygen, which allows for precise measurement of reaction rate constants (Glin and Datan 2007)
