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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (28)
Moreover, 5-hmC is also enriched within gene bodies and at intronexon boundaries of synaptic plasticity-related genes [42]
2022 Jan 19;41(1):27
ROO is another highly ROS that play a crucial role in oxidative stress, lipid peroxidation, and various biological processes
