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Most importantly, maintain close communication with your healthcare provider to adjust your protocol based on your individual response

[DOI] [PubMed] [Google Scholar] 12.Dallongeville J, Fruchart JC, Auwerx J

Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility

We argue that viewing MS through the lens of an early onset, slowly progressive cytodegeneration of white and gray matter elements, convolved with a variable overlay of adaptive autoimmunity, could readily explain the entire disease spectrum, and aligns well with emerging new evidence