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$28.41

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10.1002/ana.1256 252 NicolasA.KennaK

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demonstrated that low concentrations of APAP-CYS are detectable in serum following therapeutic dosing with acetaminophen in the vast majority of individuals

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81 In parallel, the expression of ATP-binding cassette (ABC) transporters, especially P-gp (ABCB1), MRP1 (ABCC1) and BCRP (ABCG2), expressed both on tumour cells and in the BBB, as drug efflux pumps has been proven to play a crucial role in multidrug-resistance

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