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507 However, hyperactive IRE1 signaling is also associated with -cell deficits, and ATF4 and CHOP deletion may have protective effects against -cell dysfunction or T2D, suggesting that the UPR may also mediate apoptotic signaling in stressed -cells

S.Belal ChowdhuryM.AfrinS.BurrittD

His work has appeared on other science websites, such as BBC Science Focus and Scientific American
