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acetyl-l-carnitine biological half-life JCI Acetyl-L-Carnitine | C9H17NO4 | CID

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J., Wild B., et al

acetyl-l-carnitine biological half-life JCI Acetyl-L-Carnitine | C9H17NO4 | CID

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acetyl-l-carnitine biological half-life JCI Acetyl-L-Carnitine | C9H17NO4 | CID

both 5-oxoproline (pyroglutamate, 5OXP)29 and ophthalmic acid (OPA), a tripeptide analog of GSH in which the cysteine group is replaced by l-2-aminobutyrate, have been found to reflect the effects of reactive metabolite production on the GSH depletion seen with APAP toxicity.30 For example, the excretion in the urine of large quantities (up to concentrations of 1 M) of 5OXP was observed after three weeks of feeding APAP in the diet (1%) to young rats.29 These results are illustrated in Fig

acetyl-l-carnitine biological half-life JCI Acetyl-L-Carnitine | C9H17NO4 | CID

49 (2 Suppl

acetyl-l-carnitine biological half-life JCI Acetyl-L-Carnitine | C9H17NO4 | CID

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