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Description
a recent work proposed that A1AT could signal through CD36 (a scavenger receptor expressed on monocytes, macrophages and dendritic cells), activating a phospholipase (PLA2) that in turn induces the expression of a small factor with a cholinergic activity that binds acetylcholine receptor in an autocrine manner thus eventually inhibiting the opening of the P2X7 channel (53)
Tian G, Pan R, Zhang B, et al
2008;101:14D19D
SKIN DEEP(EWG) 4
