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Typically, this is a middle-aged problem, but occupation and hobbies can be major contributing factors

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doi:10.1186/s43094-020-00086-2

Some studies have indicated the presence of a small to medium sized reduction, while others have noted no differences, or higher GSH in schizophrenia ( In recent times, meta-analysis of group variance has emerged as an important method in the investigation of therapeutic ( Greater variability in GSH levels in schizophrenia would mean that some patients (i.e., the putative low-GSH subgroup) are more likely to benefit from the use of GSH precursors or drugs that activate Nrf2 pathway than the others